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Frequently Asked Questions for Pharmacists on Safe Injection Practices / Single-Dose vs. Multi-Dose Vials

Q: What are the guidelines on single-dose versus multi-dose vials?

A: From the Department of Health & Human Services: As the normal saline (NS) 0.9% bags for injection shortage continues, please take a minute to review the One & Only Campaign.  The One & Only Campaign is a reminder of the importance for using single dose and multi-dose vials appropriately and the consequences for failing to do so.  The newest information from the One & Only Campaign is at  More information about the NS bag shortage can be found on the FDA website at:, and on the ASHP website at:  As many institutions institute conservation measures in light of the shortage, please keep in mind that  IV bags are considered single-dose and should never be used for more than one patient, even during periods of shortage.


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